Hubungan Infeksi Soil Transmitted Helmith dengan Kadar Kolesterol Darah Pada Anak dan Dewasa di Daerah Endemik Kecacingan Sumatera Barat

  • Nurhayati Nurhayati Fakultas kedokteran Universitas Andalas
  • Hasmiwati Hasmiwati Fakultas Kedokteran Universitas Andalas
  • Eka Novita Fakultas Kedokteran Universitas ANdalas
Keywords: kecacingan, STH, kolesterol darah, worm, soil transmitted helminth, blood cholesterol

Abstract

Soil transmitted Helminth (STH) merupakan penyebab tersering dari infeksi kronis pada usus manusia.  Kemampuan cacing memodulasi respon imun host melalui Th2 yang memicu sitokin anti inflamatori diduga mempengaruhi kadar kolesterol darah pada individu yang terinfeksi STH, yang akan memiliki efek protektif terhadap penyakit metabolik. Oleh karena itu penelitian ini bertujuan melihat hubungan infeksi STH  dengan kadar kolesterol darah, sebagai dasar helminthic therapy dan evaluasi terhadap program pengobatan massal. Infeksi STH diperiksa dengan pemeriksaan tinja metode langsung dengan iodine, sedangkan untuk mengukur jumlah telur per gram tinja dilakukan dengan  metode Kato Katz. Kadar kolesterol total darah diperiksa dengan metode enzimatik CHOD-PAP. Semua subjek penelitian yang terinfeksi  STH pada penelitian ini tergolong  infeksi ringan. Kadar kolesterol individu yang terinfeksi STH didapatkan lebih rendah dibandingkan kadar kolesterol individu yang tidak terinfeksi STH, baik pada anak ataupun dewasa  (p<0,05), sehingga dapat disimpulkan bahwa terdapat hubungan yang bermakna antara infeksi STH dengan kadar kolesterol darah, sekalipun pada infeksi ringan.

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Published
2021-06-30
How to Cite
Nurhayati, N., Hasmiwati, H., & Novita, E. (2021). Hubungan Infeksi Soil Transmitted Helmith dengan Kadar Kolesterol Darah Pada Anak dan Dewasa di Daerah Endemik Kecacingan Sumatera Barat. JURNAL KESEHATAN PERINTIS (Perintis’s Health Journal), 8(1), 12-16. https://doi.org/10.33653/jkp.v8i1.617